Technology

ART

What is ART (AGEs Reducing Technology)?

ART (AGEs Ruducing Technology) is our unique core technology that offers an innovative therapeutic approach by reducing the activity of Advanced Glycation End-products (AGEs).
Through this reduction, it can prevent various complications such as metabolic syndrome.

What is Glycotoxin?

The scientific term for glycotoxin is Advanced Glycation End-products (AGEs).
“Glycation" refers to the reaction in which proteins or fats combine with sugars to undergo changes.
The resulting substances are called AGEs.This reaction occurs both in food and within our bodies.

Sources of Glycotoxins

Glycotoxins & Diseases

When ingested from food or produced in the gut, AGEs bind to Receptors for AGEs (RAGEs), which are widely distributed in tissues throughout the body, triggering inflammatory responses via NFkB and leading to various diseases.
A study conducted in Italy examining the correlation between serum AGEs levels and lifespan (over a period of 20 years) among the elderly revealed an inverse relationship, indicating that serum AGEs levels and lifespan are inversely correlated.
It provides evidence that AGEs directly contribute to shortened lifespan.

Human Trials on Patients with MAFLD or diabetic steatohepatitis

We confirmed significant improvements in patients with mild fatty liver and fibrosis through the combination therapy based on FAR Tech and BAR Tech.
This outcome is particularly promising in the NASH/MAFLD field, where there is still no reliable medication available.
It also serves as meaningful evidence supporting the validity of the Metabolic Targeting and Balancing technology approach.

- Study Site: Seoul National University Bundang Hospital, Yongin Severance Hospital
- Study Subject: Patients with metabolic dysfunction associated fatty liver disease (MAFLD) or diabetic steatohepatitis